Upgrading an Oldrim DLL to work with SKSE64

[themodder2000]

First off, i'm fairly new to modding, and have recently begun using the Bethesda Creation Kit to upgrade Skyrim mods to work with Skyrim Special Edition. However some master mods from Oldrim, i've noticed, can't be upgraded, presumably because they require SKSE, and not SKSE64, and aren't compatible with the version I am using, (SKSE64 2.0.16 with SSE 1.5.80.) Installing these sorts of mods results in Vortex getting a "Script Extender Plugin Errors Detected" error, and starting the game always results in a crash.

So my question is, is it possible to modify a mod's DLL files, or files in general, (again, i'm not too good with these sorts of technical things, but I am willing to learn.) To work with SKSE64.