Skyrim LE Game/SKSE fails to start occasionally after 5-10 seconds

[NordFred]

Occasionally, when I attempt to start my game from MO1 using the Run button to start the skse_loader.exe, it fails to start very VERY early in the process. Long before saves or even mods would come into play - the main game window never opens at all. The game looks like it is starting normally for the first 5-10 seconds. I see the black "command prompt" window (AKA the DosBox) that starts SKSE open and close, but then the MO1 "Unlock button" window goes away. If I start the game again using the Run button, it usually starts up fine, although sometimes it will fail 2 or 3 times before finally working.

 

Obviously, since it works most of the time, the obvious things like MO1 configuration issues or running as Admin, aren't going to be the problem here. Most of the time the game starts normally, so the MO1 settings to start the game are setup correctly, and haven't changed for ages. My guess is that it is some kind of timing issue during SKSE startup, but I have no idea what could be causing it to happen.

 

Here is what I see at the end of the "skse_loader.log" file when the problem occurs:

 

hook thread complete
launching
WARNING: something has started the runtime outside of skse_loader's control.
SKSE will probably not function correctly.
Try running skse_loader as an administrator, or check for conflicts with a virus scanner.

When the problem first started happening, I tried checking for any running SKSE, ENB, or Skyrim/TESV tasks running just before a failed attempt, and nothing can be seen using Task Manager.

 

My game started fine the way it is currently configured for a few years before the problem started happening in the last few months.

 

If anybody has experienced this and has a fix or workaround, please let me know.

 

Thanks!

Edited November 18, 2020 by NordFred