You can actually script it to do so, but I would say it's probably not worth it. However, if you want, well, it's intriguing enough that I'll come along for the ride. I've never done it before, and it looks a bit complex, but it's pretty clearly possible.
You would want to use the FalloutCustom.ini from JIP, which will override (but not overwrite) all other settings from all other .ini files if JIP is installed. At that point, you'd essentially want to use a script that finds the .ini setting as a string, and replaces it with what you want. That is, unless there's a better way that I'm not aware of.
Here's all the JIP functions:
I've done a cursory look and this seems doable, if not quite a bit more complex than simply instructing others to modify their .ini files.
Edited by EPDGaffney, 17 January 2018 - 06:23 AM.