MikeyTK

Could be anything, really. Is it a new save? Did you add or remove any mods during the gameplay?

Deactivate some mods, start the game and check if it still crashes. Do that until you can narrow it down to one mod. Maybe start with deactivating obis and immersive creatures, those mods are known for ctds under some circumstances SSE engine fixes is installed?

Have you checked Skyland AIO? Imo the best texture overhaul. Some seams are unavoideable though. The newest enb series comes with the terrain blending feature, which weakens a lot of seams