Okay, I've downloaded the alpha and I will give it a fair roll with SSE and FO4. I'll give it a shot. But after reading all the 'Who is Vortex for?' and 'Why Vortex?' pages, I'm a little trepidatious about this: I'm told that this is for people who play games I'm not interested in, for people who don't want to manage their own load orders, but it's Modern and has Close nexus Integration. Okay, but it's not at all clear what I have to gain here. I'll keep my legacy MO setups for FNV and Skyrim. I already have profiles and close nexus integration, but I see you're planning to take that away.
I sincerely hope it's not so, but after following this for two years, it seems Dark0ne may have erred in requiring a one-size-fits-all solution. Maybe it would have made more sense to fork the development at Bethesda and non-Bethesda. More difficult, yes, but a lot more durable. No offense intended, just an outsider's view. Time will tell and I do hope I'm wrong.
All the best, ff