What helped me was Sweetfx. Before Sweetfx I got massive headache everytime I played. Sweetfx seems to make background sharper, which helped me. Now I dont need to take painkillers to keep playing lol, but most of my time I still play in third person watching horizon. To me key is to watch something that doesn't move, like horizon. So yeah, Sweetfx helped me. I used that guide to install Sweetfx, using same settings as shown in guide. "TAA + Sharpening" "LUMASHARPEN - SweetFX" - http://www.tweakguides.com/Fallout4_1.html There seems to be now mod that installs it also. http://www.nexusmods.com/fallout4/mods/40/?