I just did the NMM Update and am having the same issues. I am running windows 7 64 Bit, when I try to open Nmm it comes up saying that I need .NET 4.6 I've tried the link NMM gives but it comes up not compatible. I have even gone so far as to go to the MS website and downloaded 4.6 and 4.6.1 64 bit, but every time I try to install it comes up with a window saying: Blocking Issues: The .NET Framework 4.6.1 is not supported on this operating system. What is better in 4.6 than an earlier version? Why do those who can't update for some weird in-compatibility issue have to be forced to update when we can't?