I'm very new at this, but I have a feeling I should have just stayed away until all the bugs were worked out of the system... I have latest Beth patch, latest NMM installed, reinstalled all of the mods i had, have all UI mods disabled, done as many fixes as y'all have suggested within my very limited knowledge... I can load my saves, but I just randomly CTD while in-game. 3 times leaving a building and 1 time when I came upon the alien crash site. It also randomly disables my plugins in the game menu. I don't really understand whats going on, but I hope that things will stabilize soon.