I used vortex to mod fallout4 with 400ish mods and it worked fine for me. With Skyrim SE I use NMM (It takes a bit of planning and understanding how it works). NMM I am using 681 mods for Skyrim SE no issues. I think it is great to have choices since some MM do things better then others and some worse then others but all 4 MM's (NMM, MO2, Vortex and Wrye Bash) are great! just depends what game and you understanding what you are trying to do!