Thanks for responding Mike. I *think* I might have found what was causing the issue. I had just gotten to Bitter Springs in game, and everytime I approached it I would either crash about 50 yards away from it, or if I made it to Bitter Springs the npc's had no sound, and other sounds were missing in that area as well. I went back to a vanilla location and the npc's sound, etc was working. So I deleted the Bitter Springs revisited mod, as well as all the other NPC mods I had installed. Went back to Bitter Springs, sound was working, and I haven't crashed since I deleted those mods in roughly 60-90 minutes of gameplay (which is huge after crashing every 2-3 minutes previously). Definitely not saying the NPC mods alone were causing my crashes, could have been a conflict with other mods, I'm thinking the Bounties mods & the NPC adding mods didn't get along, probably due to both adding additional NPC's to the world. So deleted both, and the world is definitely not as fun without the Bounties mods, but I can play now. I don't think it was Bounties alone causing my issues, as that is one of the top files on the nexus for Fallout NV and many people seem to have no issues with it. Thanks for the info on how to backup the folders to save mods if (when) I need to do a reinstall of this or other games.