i just had an issue with that and was very happy that the solution was that easy. not as easy as it should've been but anyway... IF you have a calibrated monitor, skyrim should work just fine with your profile. however... if you're an idiot like me, you might for some reason alter the brightness-setting ingame. which makes the game override your profile with its own, probably based on the default srgb-profile. and as there is no "reset to defaults" button in the options, which would get rid of that override, you have to go into the ini-files yourself. just remove the following line from SkyrimPrefs.ini and you should be good to go again: "fGamma=[...]"