In order for the mods to work, you need to launch the game through NMM, using the option to launch FOSE. If FOSE was installed correctly, which is a manual install, the option will appear in NMM where you would normally launch the game. If you are using Steam to handle the game, there is some workaround necessary. I use neither NMM nor Steam, but have seen posts explaining how to get Fallout 3 to launch through FOSE with Steam. Oh, thanks for the answer. I'll try to do that. One thing: is there a way to make a shortcut using the NMM? Or I'll need to open NMM and execute FOSE through it everytime I want to play FO3?