It's an install order problem. For me, I corrected it by: 1. Uninstalling DarN UI and hotfix all together 2. Disabled all other Hud mods (Immersive HUD, Unified HUD, FWE Darnified patch, etc) 3. I then reinstalled DarN UI fomod version, then it's hotfix (Saying yes to All for each when prompted) 4. Then installed the DUI patches for any mods that have them (Saying yes to All) 5. Then activated each of my other Hud mods (Saying yes to All) This seemed to work, as I started the game and whether I continued or started a new game, the DUI help screen didn't show up when I hit ESC. Just the DUIF3 menu at the lower right appeared, as it should, and I could access the settings menu. Hope this helps.