LeonardDeVir

I want to add another little interesting trick. If you ever happen go get stuck on an interior-exterior transistion ( = game wont load an exterior) ....open your map, zoom in and wiggle around a bit (RMB and move around). No really. For one weird reason opening the map seems to load bits of the outside area which helps the engine load the "world" exterior properly on the transistion. Which means, you may be able to leave your prison of a city/house/dungeon if you get stuck when trying to leave it. Dont ask me, stumbled upon it by accident.

150+ mods is quite a lot; ever tried to reduce your load order to ~100 active mods? It sounds like you hit your personal mod limit - if your load order hits a certain number, things start to get funky. Crashes, objects vanishing, main menu not appearing,... I really recommend you to: 1) look at a mod compilation, like Mission Mojave - Ultimate Edition. As far as Ive read, loads of your mods are rather small fixes which may be/are incorporated in MMUE. Bonus points: everything is optimized to work properly which each other. 2) make a bashed patch with Wrye Flash. DONT use the merged patch from FNVEdit - this tool is too old any might screw you over. I see you know how to use BOSS; get the bashed tags from it, mark the mods accordingly in Wrye Flash and let it create a bashed patch. Usually there is no harm in doing so, it WILL reduce your load order significatly and it makes sure that important edits are rally loaded into the game.