I'm attempting it now on a save with a 60+ lvl character with 140+ mods, tweaks, and changes. I gave it some thought, began thinking of other things, then just went for it. See, this is why I don't drink. I'm capricious enough when I'm sober. Huzzah!... and stuff... Edit: It went exactly as I thought it would. I needed a new install anyway. My game folder had the clap. Edit 2: Thanks to surviving my past misadventures and a file hoarding habit I should be able to get my old save up and running in about 3 hours. That's my old record. I think I can beat it. Dunno if I'll finally try MO or try NMM .6. I'm not mad since I constantly bork my own installs.