Something I figured out is that while I have the Vortex client open while playing Skyrim SE the save times are really long. I timed it at around 23 seconds opposed to the usual 3 or less. And this is any type of save: quicksave, autosave, and manual save. Personally I don't see this as a big issue and I haven't experimented with it much nor do I desire to find a fix. I just close Vortex before playing, it closes and boots up very quickly so it isn't an annoyance. I'm just curious if this happens to anyone else or it's a known issue/bug. If you want specific info to try and recreate the occurrence tell me what you want to know, I might remember to check this forum.