Simple tip here, and I'm talking abut experience. When I first got into moddng, I jumped and installed a ton of mods, simultaneously, very bad idea, ran into bugs, and was unable to find the culprit, so if modding, install mods one by one, and see how it turns out. But back on the problem, I see you're using HDT, I've seen some posters complain about it gradually degrading performance. So before you uninstall everything, deactivate HDT first and see how it is.