My PC is on 24/7, I click the Steam icon, then, while it's doing it's thing, start NMM, click the start FO4 button at the top of NMM, then go downstairs and make a coffee. Come back up, drink coffee, by which time I can select "click any button to start" I moved Fallout 4 to a spare SSD and finally worked out how to install NMM 0.61.14 and now it starts in about 15 seconds, so a HUGE improvement.