Hello all! I am running Windows 10 Tech Preview, and Nexus Mod Manager keeps crashing on launch. I've figured out my issue, so I figured I'd clue you guys in: I needed to force NexusClient.exe to run in 32-bit mode. To do this, I needed a command-line program called CorFlags.exe, which is included in the .NET 4.5 SDK. With Administrative privileges, run: CorFlags.exe "C:\Program Files\Nexus Mod Manager\NexusClient.exe" /32Bit+ I will note that the stack in the exception thrown is similar, though slightly different, from the one in the first post. From the Event Log: The issue in the first post was an exception thrown on ReadByte, whereas mine was thrown on ReadInt64. Same exception though, maybe it's the same issue?