So.... in the recent days i started having some major issues with Skyrim CTD almost on a regular basis, enough for me to want to pull my hair out, i was on the last leg of defeating Alduin, and everytime i traveled on the dragon i would get a instant CDT, So i started brainstorming possible issues, Mods conflicting? wrong mod order? I decided to start with a clean slate, i used my smart phone to remember what mods i had installed and then began removing every single mod from the game, and uninstalling Skyrim, I made copy's of my save files for my characters and saved them to desktop, I then went through and deleted every file associated with Skyrim on my Hardrive. So thus after completetly erasing my game from my computer i went and did a security scan and sure enough, somehow my SKSE got corrupted with a Virus that was conflicting with the DLL"s needed to run it smoothly with Skyrim, then i did a full registry repair and found multiple issues, it also turns out my Antivirus was not doing it's job so i uninstalled that also and put a better program, my favorite antivirus of choice is Avast, i have never ever had any issues running it, and as a user for close to ten years i stand by it. Anyways not to get off track, after adding new Antivirus and doing a full registry scan and fixing every possible issue, i started the task of reinstalling Skyrim, then i began installing my mods starting with my Character creation mods, CHBC, CBBE Ect. and to my amazement after i finished reinstalling all of my mods and reinstalling SKSE, my game runs like brand new, i have had 0 CTD"s. I know there are far more advanced players on here, i just wanted to share this so if you're having the same issues i was, be sure to check your PC, Yes Skyrim has it's issues but before throwing in the towel, you may have a conflicting program which is making your life miserable. Hope you guys have a great day!!