In reality, after 200 years the wasteland would have been overtaken by nature, and there wouldn't actually be all that much radiation left. Keep in mind, Chernobyl emitted so much radiation that the nearby forests died and turned red, but nature has already fully taken it all back to some extent and animals live there. Chernobyl was a nuclear power station, and used significantly less enriched nuclear fuel than nuclear weapons do. Nuclear weapons are very highly enriched which allows them to do astronomical amounts of damage, but doesn't actually emit enough radiation to last particularly long. Hiroshima and Nagasaki are the only two instances of nuclear weapons being used in war, and both are now bustling, vibrant cities with no radiation other than normal background radiation. So no, in reality it would not look like it does in Fallout 4. A single nuclear bomb, as seen in the intro to Fallout 4, would certainly not have been capable of creating anything remotely as bad as the Glowing Sea.