after the 1.4 patch, i updated SKSE and removed SkyBoost. upon playing the game i was getting CTDs for the first time in months, my framerates were constantly dropping into the 20s (i have a powerful rig and used to play at 50+ at all times), and i was getting odd glitches and random wierdness. after reading a ton of posts about this, i decided to take a scorched earth approach. i uninstalled Skyrim, uninstalled NMM, then went to my Steam\Common\Skyrim folder and deleted it, then went to my C:\Games\Skyrim folder and deleted it, then deleted everything in the Documents\My Games\Skyrim folder *except* for the Saves folder, which I left alone. next i uninstalled my video drivers, and installed the latest version, defragged my HDD, and rebooted my system. after that i reinstalled Skyrim, let Steam install all of the patches, edited my .ini files to my preferences (7 uGrids & some other minor tweaks), installed NMM, SKSE, and then reinstalled most of the mods i was using (SkyUI, SkyrimHD, and many others - but NOT SkyBoost which does not support patch 1.4). i loaded up the game and behold - i get a solid 50-60 FPS everywhere, on Ultra, everything maxxed, 7 uGrids, and this time i installed the Full version of SkyrimHD, whereas before i was running the Lite version. so - even though i was SURE that the patch borked the game, it turns out that it was something that i did, or that one of the mods i was using did, or one of my .ini tweaks. the point is - it was my fault and it was fixable. to all of you who are experiencing issues - did you try doing what i did? and i mean everything - especially deleteing the folders (just uninstalling and reinstalling does NOT create a truly fresh install). if you haven't, then i suggest you try it. it took me several hours, but it was worth it to play Skyrim in glorious HD at rock-solid FPS after the work was done.