Hi, I also just in the last 2 week have been having the same issues, randomly 2 of my 3 monitors would lock up turn off with no video signal the third however (on another V/card) I could continue to see but my pc was locked up, a hard reboot was the only choice. (with the Skyrim sound playing on for a while.) Oh I run Win 7 64 bit. I run CPUID HWMonitor on the monitor I could watch even after the crash locked up my PC, it still showed me that display and I noticed my video card was over heating (92`c) I took the side off and stuck a desktop fan there to cool everything and ran the game for several hours (with it blowing air in it) (with the temp staying around 56`c) without a lockup compared to early that day when I was locking up every 10 to 15 mins or sooner. I have no idea what changed and why I use to be able to play Skyrim without this extreme fix but for me seems its the issue. (have to look at other cooling don't want a desktop fan there fulltime) Hope this helps you. :)