There's a difference between Install Order, which is in which order you install your mods and Load order, which is the order in which the game loads them in as needed. It helps to keep that in mind. As for how to go about it: I always do big fixing things like the Unofficial patches etc first, and then other little bugfixes etc.Then I do UI stuff and THEN quest stuff and things like Falskaar and expansions. Bigger things like Frostfall, Complete Alchemy and Crafting or Perk Overhauls etc I install relatively late after I've done all the clutter and texture mods I want to use. With tools like LOOT and the like, Unless you know exactly every esp or esm and what is what then it always helps to at least run them to give you a base load order. You can then tweak it if that's what you prefer, that's fine. I often do this myself. And you can rest assured with save cleaner that it's perfectly clean, I don't have a huge issue with script lag. I don't mess with Papyrus really at all aside from tweaking fPostLoadUpdateTimeMS to 2000. That stops the occasional little issue like Uthgerd not rendering when talking to the stable guy at Whiterun, yet her voice still playing like she was there.