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fallout4.esm is inactive


CyberSoundWave1977

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The message says to me that the core game ESM is either completely missing or not in your plugins.txt file. More likely the former.

 

If Vortex's plugins tab also failed to load then you've probably got something on your PC that breaks the game and anything the manages it (probably anti-virus apps).

 

In Vortex go to Extensions and search for Gamebyro Plugin Support, if it's disabled double click it to see the error. In most cases an anti-virus app will strip away a core file needed to make it work which requires a reinstall of Vortex to fix.

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