Zanderat

Not Vortex's fault.  I have modded DAO quite a bit .  Some of the older mods need to be repacked to work with Vortex or only work with DAO-ModManager

update: MacSplody (on discord) confirmed that some LOOT groups were removed and replaced with new groups.  Not really a Vortex issue.

Possible fix.  Unfortunately, with the new forums, I can't link to it.  The fix is on the SSE Engine Fixes page in the current post by Hadariel101, timestamp is 06 December 2023, 4:54AM

The game and Vortex staging folder must be on the drive.

I would purge. Delete the contents of the Data folder, re-validate/repair in STEAM to get back anything accidentally deleted, then redeploy.

??????? Vortex already has file specific conflict management:

SSE has been updated to v1.6.xx. AE is a paid for DLC expansion pack, which includes the SSE update. There is no need for a separate section.

Yes. Double click on a mod and in the panel that opens on the right, you can do this.

You don't mention which game is giving you trouble. But load order changes won't corrupt a save for TES/FO games.

Not a Vortex issue. Ask on this presets page.

Ok. You know best.

Oblivion mods are hit and miss. There weren't a lot standards back then. The resource file specifically looks like it is set up for Wrye BASH. If it were me, I would repack it to be modern mod manager friendly (Vortex or MO2).

No. Pick one and stick with it. If you decide top use stand alone LOOT, make that you turn off auto-sorting on the Vortex plugins page.

If it were me, I would:
PURGE any mod installed WITH Vortex Manually delete any non-vanilla files from your Data folder. If in doubt, delete it. Repair/verify your game with STEAM, to restore any accidentally delete vanilla files. At this point, your game should be back to a functioning vanilla state. Test with a new game to make sure everything is OK. You can use LAL (and its requirements) to skip the intro/Helgen. Install SKSE64 with Vortex. Test to make sure that you installed it correctly. Hit deploy to add back your purged mods. Test again. Hopefully, everything works. If you still have issues, DISABLE all your mods. Add back a few at a time (install then deploy) and test each time, until you have an issue. That way, you have at least narrowed down the problem and it will be easier to find. Good luck.

I know your monitor 144hz but 60 fps is plenty for this game.

https://wiki.step-project.com/Project:Skyrim_Special_Edition is good. They recommend MO2 but Vortex has the same functionalities and is easier to use.

@Tannin42. I see that this was added in ver. 1.2.6. Thanks!

Look, you can and should use Vortex to install your mods. However, it is NOT a requirement to run any game through Vortex to use mods. After you have installed any mods, close Vortex and run TW3 the normal way. Same goes for any other game.

Deploy

RTFM