PC I have on-board realtek 7.1 sound, and USB Logitech 7.1 G35 Headphones I switch between the two depending on what I'm doing, if I'm watching YouTube videos, I'll set the RealTek onboard sound as the default device, if I'm gaming I'll set the Headphones as the default device. This is the only game where I've had this problem. It seems if text is being displayed next to the cursor, (IE contents of a body, container, safe, etc) at the same time something is looted my game will freeze. Ok, I was only asking because I had Creative's X-Fi Titanium card for years that gave me good service until I found it causing too many CTD's and lockups in this game. After removing it and of course the drivers for it too, and reverting to my motherboards realtek sound chip, the CTD's and lockups have been reduced significantly so far. Its inferior sound quality imo but it makes for smoother gameplay experience so I shouldn't complain. All this after Creative released win10 drivers for this card too. However, steam released another update patch for FO4 yesterday, so I"m yet to see how much more stable and CTD free this game is...