SKSE is skyrim script extender wich is a program that makes your skyrim faster and more moddable, SkyUi is an interface for your mods (it's for when you press esc in skyrim) SKSE you can download through the site http://skse.silverlock.org/ just download the newest version and run the file, SkyUi is just a download from the nexus like normal mods,1 push download button, 2 install the mod when modding always check for requirements since they crash your game if they're not there