Wolvenna

If you run into a problem like this again, a simple solution is usually to run LOOT again (if you haven't already) and make sure that texture/mesh altering mods (like SMIM) are overwriting everything else when they're installed. ModOrganizer makes this easy to do, but back when I was using Nexus Mod Manger I would manually reinstall mods that might be causing an issue like this and tell them to overwrite everything. It was tedious, but it worked.

It sounds like you might benefit from running ENBoost if you're not running it already. Skyrim wasn't designed to take advantage of larger Video Cards with lots of VRAM. From your load order it looks like you're already running ENB so here's a quick video about turning on and tweaking your settings for ENBoost, I hope it helps. I'm not 100% certain that it will fix all of your problems, but it certainly can't hurt.

derp. I'm blind. Sorry about that.

By Instant CTD do you mean right after the Bethesda logo? If so, then that's caused by a missing master file. Meaning a mod you've got installed relies on another mod that's not present or is getting loaded after it. LOOT usually takes care to make sure that mods are loaded after the mods they're dependent on. So that probably means you're missing a plugin. I only glanced over your load list because it's kind of hard to read it the way you've got it. I'm not seeing the Static Mesh Improvement Mod (SMIM) in your list, but you've got several plugins that seem to rely on SMIM. Might be a place to start... What mod manager are you using?

I use SFO and Verdant together without issue in my mod set up, but I don't recognize the Grass Variants.esp in your first picture. Try disabling that and see if it goes away.

MO isn't that hard to learn. It's actually a lot more intuitive than people give it credit for. It makes it very easy to correct things and make sure everything's cleaned up properly. As for your current situation. If your game is running fine and Interesting NPCs is working now, then there shouldn't be a problem. Unless I'm not understanding your post.

So because you've got the Memory Blocks Log I'm going to assume you've turned on SSME by creating the SKSE.ini file. Have you installed ENB and turned on ENBoost?

The easiest way to answer this question would be to download them both and check it in game yourself. From what I remember I don't think they conflict too much. The worst that would happen is you get some item clipping even if they did overlap.

Looks like missing textures. I'm not sure what for at the moment. Spell impacts maybe?

Have you tweaked the SkyrimEditor.ini to let you load multiple masters?

I'm not sure if this will solve all of your issues, but Quick Load and Quick Save are probably the worst way to save/load your game. They're known to be unstable and not work properly.

Okay so a couple of thoughts; You have RacemenuMorphs is this the Bodyslide plugin? I only ask because I'm not familiar with bodyslide so I'm not 100%. However, it looks like it is loading before Racemenu when I'm pretty sure that if it's a plugin for Racemenu it should load AFTER. Second thought, if the Racemenumorphs is part of bodyslide then I think you need something like the XP32 skeleton installed.

Well what mods do you have installed? It's kind of hard to help if we don't know what might be causing the problem.

Is this the ENB that you're talking about? If it is, it requires ENBhelper.dll and you didn't mention that in your post so I'm going to assume you don't have it. You can download it from here

Do you have SKSE installed? And have you turned on SSME?