If your SKSE64 is not working, you either, have a mismatch with the SkyrimSE.exe or you have installed it wrong. Some people don’t pay close enough attention to which version they are downloading, make sure that’s not you. Current SE build 2.0.17 (runtime 1.5.97) Runtime meaning SkyrimSE.exe’s properties/details shows product version 1.5.97.0 On a side note, SkyUI is NOT version specific, it works with any and all SKSE64 versions.