Rattledagger

ctrl+a, choose "Remove" to uninstall all mods. If you also wants to delete the mod-archives choose "Delete archive" in the dialogue that opens-up after choosing Remove on all mods. To be even more extreme, you can also delete all save-games and delete all profiles.

In the off-chance you're using some kind of FAT as the disk system you also can't use hard-linking as deployment-method. Some external drives seems to use exFAT.

Step 1 means where's less files to move by Steam and this means this step goes faster. In addition if you don't purge beforehand (or switch to a blank profile), it is a possibility some files is not correctly tracked as added by Vortex later on. Step 7 is critical, since if you don't use Vortex to move "Mod Staging Folder" it's a very good chance all installed mods will be duplicated. An additional step 7b would be "make sure deployment method is "Hardlink deployment" (Vortex - Settings - Mods). Until Vortex adds a method to export all rules etc. and later import these again, I'm not aware of any better method to move mods between disks.

As long as you uses Vortex to move the mod staging folder, you shouldn't need to re-install anything and all the rules you've created should still be working. If on the other hand you moves the mods manually, all mods will likely be duplicated and you'll lose all the rules (except the ones on plugin tab). Now, where is a possibility something goes wrong with Vortex moving the mod staging folder, in this case the best is to re-install all mods and this means you'll need to re-create the rules, but at least the few times I've changed between disks I've not had any problems.

Game and mod-folder must be on the same drive, so you should do something like: 1: In Vortex, on mods-tab hit "purge". 2: Exit Vortex. 3: In Steam, move Skyrim to another drive. 4: Run Skyrim launcher once to setup registry etc. 5: Re-start Vortex to detect new location of Skyrim. 6: Just to be on the safe side re-start Vortex. 7: In Vortex click Settings, Mods, specify new location of "Mod Staging Folder" on the new drive, and Vortex should move all files for you. Note, this can take a long time. 8: On mods tab, Deploy.

Based on https://loot.github.io/search/ where are 4 entries about Horizon in the Fallout 4 LOOT master list, all has to do with some kind of Homemaker-patch. So, apart for this patch may or may not work correctly, for the rest of Horizon, just put Horizon into the last LOOT group and things should work.

If you want to uninstall all mods, it's also possible to exit Vortex, delete the game folder and delete all contents of games "staging folder" (but just to be on the safe side keep the staging folder). This will keep all the mod archives but you need to redownload the game.

If you've just switched to mods-tab or plugins-tab it won't work, you need to select one of the mods/plugins first before ctrl + a works.

On mods-tab, select one of the mods and hit ctrl + a and you can enable/disable/install/re-install/remove all mods. It's the same for plugins-tab but here you can only enable/disable all plugins. Two other common selection-methods is to use shift + mouse or ctrl + mouse.

Some games from 2000 - 2004 doing this includes Nox, Morrowind and Doom 3. In the same period where's also a few games putting save as one sub-directory (often under uninstall) and application as another sub-directory. These includes Deus Ex and Gothic 1 + 2.