The settings "Starter" and "Recently Managed" are already on.
As for moving the game. The only drive I have available is the local disk. Vortex and Steam are located in the x86 program files. I take it you are suggesting to move everything from x86 to the basic program files?
you need to install the Vortex version that allows you to install where you want.
Install everything outside of ANY "Program Files" folders because Windows protects them too much.
Install your Steam and Games in their own folder like C:\Steam
Install Vortex into it's own folder
And set your Mod DOWNLOAD Folder, and Mod STAGING folder into their own folders OUTSIDE of any "Program Files" folder